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Understand the disease

Parkinson's Disease

The second most common neurodegenerative disease after Alzheimer's, Parkinson's disease affects people of all ages — including young adults, still in full professional and family life. To better understand it is to better support it.

Tulip

272,500

Patients in France

or 0.4% of the population

27,000

New cases

diagnosed each year

> 10%

Are under 50

early-onset forms

2nd

Neurodegenerative disease

most common in France

Physiopathology

What is Parkinson's disease?

Parkinson's disease is a progressive neurodegenerative condition characterized by the destruction of dopaminergic neurons in the substantia nigra, a small structure in the brain located in a region involved in the proper execution of movements.

Dopamine is a neurotransmitter essential for coordinating movements. Its depletion leads to characteristic motor symptoms, but also a wide variety of non-motor symptoms that often precede diagnosis by several years.

The disease progresses in stages and varies greatly from person to person. While it is not yet curable, medical and non-medical treatments can preserve quality of life and autonomy in the long term.

Parkinson's disease also affects younger people

About 10 to 17% of cases are early-onset forms (< 50 years old), affecting people still in full professional activity. These patients have specific needs, often poorly covered by traditional tools.

Hands
Symptoms and clinical signs

Signs and symptoms of the disease

Parkinson's disease is a systemic pathology whose manifestations go far beyond the motor sphere. Here is an exhaustive overview, organized by major families.

The parkinsonian triad — 3 cardinal signs defining the diagnosis
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Resting tremors

Involuntary rhythmic movement (4-6 Hz), usually in the hand. Characteristically present at rest and diminishing during intentional movement. Often a revealing sign, but absent in 20 to 30% of patients.

⊥

Muscle rigidity

Resistance to passive mobilization of limbs, called 'lead pipe' giving way with a 'cogwheel' phenomenon. Can lead to pain, cramps, and functional discomfort. Always asymmetrical at the start of the disease.

◎

Akinesia / Bradykinesia

Slowness (bradykinesia) and reduction in range of motion, or even their absence (akinesia). Principal factor of functional handicap in daily life — daily gestures, writing, walking, speech.

Other motor symptoms

Postural instability

Impairment of postural reflexes leading to balance disorders, increased risk of falls...

Freezing of gait

Episodes of sudden foot blockage, particularly in narrow passages or at the start.

Festination

Involuntary acceleration of step with reduction in stride — risk of falling forward.

Micrographia

Writing becomes smaller and shaky, especially at the end of a sentence.

Hypophonia & dysarthrie

Weak, monotonous, or rushed voice.

Swallowing disorders

Difficulty swallowing, sometimes associated with speech disorders.

Non-motor symptoms

Depression & anxiety

Affect 40 to 50% of patients. Depression can precede motor signs by several years.

Sleep disorders

Insomnia, REM sleep behavior disorder (RBD), excessive daytime sleepiness.

Cognitive disorders

Slowing of thought, difficulty concentrating, executive function disorders.

Chronic pain

Often undervalued, linked to many factors.

Digestive disorders

Constipation, gastroparesis, nausea linked to dopaminergic treatments.

Care pathway

multidisciplinary care

Due to the diversity of its manifestations, Parkinson's disease requires the coordination of many healthcare professionals. This multidisciplinary approach is now recognized as the reference by the French National Authority for Health (HAS) and European recommendations.

Coordination between these different actors is often the principal challenge of the care pathway. Information fragments, clinical signals are lost between two consultations spaced several months apart.

This is precisely why DiamPark 360 was designed: to create a digital thread between all care actors.

Multidisciplinary team

Neurologist

Diagnosis, prescription of therapeutics, monitoring of progress.

General Practitioner

Coordination of care, renewal of prescriptions, management of comorbidities.

Physiotherapist

Motor rehabilitation, postural balance, fall prevention, mobility maintenance.

Speech Therapist

Management of speech, voice, and swallowing disorders.

Psychologist

Emotional support, cognitive therapy, support for the patient and caregiver.

Nurse

Therapeutic education, treatment management, link between patient and team.

Occupational Therapist

Adaptation of home and daily activities to maintain autonomy.

Social Worker

Access to aids, orientation towards support structures.

Dietitian

Prevention of malnutrition, management of food-drug interactions.

Hands typing
Continuous monitoring

Why monitoring is essential

Parkinson's disease is characterized by significant fluctuations during the day — the famous 'on/off' periods — and between consultations. Medical appointments, spaced a few months apart, do not always allow for capturing the complexity of these daily variations.

Therapeutic optimization

Continuous monitoring allows for adjusting medication doses and schedules according to real patient fluctuations.

More informed clinical decisions

The doctor arrives at the consultation with a complete and objective history — and not a partial memory reconstruction.

Time saving in consultation

Less time spent reconstructing history, more time for medical decisions and the patient-provider relationship.

Serious Game · Therapeutic education

Motiv'Park : playing to learn

Motiv'Park is DiamPark's serious game dedicated to therapeutic education in Parkinson's disease. Designed for patients, caregivers, and providers, it transforms learning into an engaging and accessible experience.

Understand one's disease

Interactive modules on pathophysiology, symptoms, and treatments.

Adopt the right behaviors

Situational exercises to integrate therapeutic reflexes into daily life.

Strengthen compliance

Gamification increases adherence to treatments and rehabilitation programs.

Discover Motiv'Park

Motiv'Park

The serious game for Parkinson's therapeutic education

Patients · Caregivers · Providers

DiamPark supports every step of the Parkinson's journey

Discover how our digital solution integrates into multidisciplinary care to improve patients' daily lives.

Discover the Digipark solution
DiamPark

Digital solution dedicated to Parkinson's disease. Class I medical device compliant with European Regulation (EU) 2017/745 on medical devices.

It does not replace the consultation with a healthcare professional.

Read the instructions carefully before use.

Developed in France with Passion

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